Titoli e pubblicazioni
Use of Platelet Rich Plasma (PRP) and Hyaluronic Acid in Treatment of Extremity Gunshot Injuries: A CaseReport
In the view of efficiency and cost effectiveness the increasing incidence of gunshot wounds demands a modification of treatment protocols. The general basis are antibiotics, fracture stabilization and debridement of soft tissue injuries. The pathology of gunshot wounds and established treatment algorithm however have to be adjusted to the ongoing development of gun technology and the thereby caused specific lesions. In most of the cases it is difficult to obtain a complete healing, because of the complexity of different tissues. Moreover the presence of foreign bodies and the tendency to develop infections, slow down the healing process.
Archivio
Nov – 2015
One-stage reconstruction of scalp after full thickness oncologic defects using a Dermal Regeneration Template (Integra®)
Barbara De Angelis, Pietro Gentile, Eleonora Tati, Davide J. Bottini, Fabrizio Orlandi, Giampiero Pepe, Valerio Cervelli, Ilaria Bocchini, Giulio Cervelli. Chiara Di Segni “BioMed Research International”
The use of Dermal Regeneration Template (DRT) can be a valid alternative for scalp reconstruction, especially in elderly patients where a rapid procedure with an acceptable aesthetic and reliable functional outcome is required.
Ott – 2014
LIMB RESCUE: A NEW AUTOLOGOUS-PERIPHERAL BLOOD MONONUCLEAR CELLS TECHNOLOGY IN CRITICAL LIMB ISCHEMIA AND CHRONIC ULCERS.
De Angelis B, Gentile P, Orlandi F, Bocchini I, Di Pasquali C, Agovino A, Gizzi C, Patrizi F, Scioli MG, Orlandi A, Cervelli V. Tissue Eng Part C Methods. 2014 Oct 23
Therapeutic angiogenesis by autologous-peripheral blood mononuclear cells (A-PBMNC) implantation has been shown to be a safe and effective treatment for critical limb ischemia (CLI).
Gen – 2014
Adipose-derived stromal vascular fraction cells and platelet-rich plasma: basic and clinical evaluation for cell-based therapies in patients with scars on the face.
Gentile P, De Angelis B, Pasin M, Cervelli G, Curcio CB, Floris M, Di Pasquali C, Bocchini I, Balzani A, Nicoli F, Insalaco C, Tati E, Lucarini L, Palla L, Pascali M, De Logu P, Di Segni C, Bottini DJ, Cervelli V. ; J Craniofac Surg. 2014 Jan;25(1):267-72.
Actually, autologous fat grafts have many clinical applications in breast surgery, facial rejuvenation, buttock augmentation, and Romberg syndrome as well as a treatment of liposuction sequelae.
Dic – 2013
The use of infrared radiation in the treatment of skin laxity.
Felici M, Gentile P, De Angelis B, Puccio L, Puglisi A, Felici A, Delogu P, Cervelli V. J Cosmet Laser Ther. 2013 Dec 14.
Cosmetic surgery and medicine are extremely interesting fields for a plastic surgeon. Lasers and lights determine ablation, contraction and regenerating stimulus in skin tissues. The aim of this study is to examine the use of infrared lights in treating facial and body skin laxity.
Set – 2013
P.R.L. platelet rich lipotransfert: our experience and current state of art in the combined use of fat and PRP.
Cervelli V, Bocchini I, Di Pasquali C, De Angelis B, Cervelli G, Curcio CB, Orlandi A, Scioli MG, Tati E, Delogu P, Gentile P. Biomed Res Int. 2013;2013:434191.
The authors report their experience about the use of P.R.L. PLATELET RICH LIPOTRANSFERT method (platelet rich plasma mixed fat grafting) in 223 patients affected by soft tissue defects (ulcers, Romberg syndrome, Hemifacial atrophy, loss of substance, and signs of aging).
Ago – 2013
Chronic ulcers: MATRIDERM(®) system in smoker, cardiopathic, and diabetic patients.
De Angelis B, Gentile P, Agovino A, Migner A, Orlandi F, Delogu P, Cervelli V. J Tissue Eng. 2013 Aug 26
Diabetic ulcers and pressure ulcers represent a more frequent cause of chronic wounds in aging populations. It is estimated that approximately 15% of the diabetic population will develop diabetic ulcers during their life and over half of these patients develop an infection, often osteomyelitis, with 20% requiring amputation.
Feb – 2013
The use of a non cultured autologous cell suspension to repair chronic ulcers.
De Angelis B, Migner A, Lucarini L, Agovino A, Cervelli V. Int Wound J. 2013 Feb 28.
The purpose of this uncontrolled study was to evaluate the clinical effectiveness of ReCell(®) system in the treatment of chronic ulcers. From October 2011 to July 2012, 20 patients, 8 men and 12 women with a mean age of 70 years, with chronic ulcers of different aetiology that were unresponsive to conventional therapies were recruited and treated using the ReCell(®) system.
Set – 2012
Spontaneous clostridial myonecrosis after pregnancy - emergency treatment to the limb salvage and functional recovery: a case report.
De Angelis B, Cerulli P, Lucilla L, Fusco A, Di Pasquali C, Bocchini I, Orlandi F, Agovino A, Cervelli V. Int Wound J. 2012 Sep 13
Clostridial myonecrosis (CM) is a rare, life threatening necrotizing infection of a skeletal muscle caused by Clostridium perfringens in the majority of cases. The diagnosis may be difficult because of few diagnostic and cutaneous signs early in its course.
Giu – 2012
Regenerative surgery of the complications with Morton's neuroma surgery: use of platelet rich plasma and hyaluronic acid.
De Angelis B, Lucarini L, Orlandi F, Agovino A, Migner A, Cervelli V, Izzo V, Curcio C. Int Wound J. 2012 Jun 14
Morton’s neuroma is an entrapment neuropathy of the plantar digital nerve. We treated five patients with wound dehiscence and tendon exposure, after Morton’s neuroma surgery excision using a dorsal approach.
Mag – 2012
Combined use of super-oxidised solution with negative pressure for the treatment of pressure ulcers: case report.
de Angelis B, Lucarini L, Agovino A, Migner A, Orlandi F, Floris M, Cervelli V, Curcio C. Int Wound J. 2012 May 24
A 61-year-old patient was affected by flaccid paraplegia for 20 years because of post-traumatic medullar injury caused by an accidental fall, with stage IV sacral pressure ulcer for 3 years.
Ago – 2011
Skin necrosis of scrotum due to endovascular embolisation: a case report.
Cervelli V, Brinci L, Palla L, Spallone D, Izzo V, Curcio CB, Lucarini L, De Angelis B. Int Wound J. 2012 Feb;9(1):70-5. doi: 10.1111/j.1742-481X.2011.00847.x. Epub 2011 Aug 31.
The aim of our case report was to analyse the results obtained with the Matriderm® system and autologous skin grafting for the surgical treatment of skin necrosis of scrotum as a result of endovascular embolisation.
Mag – 2011
The use of MatriDerm® and skin grafting in post-traumatic wounds.
Cervelli V, Brinci L, Spallone D, Tati E, Palla L, Lucarini L, De Angelis B. Int Wound J. 2011 Aug;8(4):400-5. doi: 10.1111/j.1742-481X.2011.00806.x. Epub 2011 May 12.
The aim of this study was to prove the effectiveness of MatriDerm(®) combined with skin grafting versus skin grafting alone in post-traumatic wounds treatment. At the Department of Plastic and Reconstructive Surgery of the University of Rome Tor Vergata, we treated 60 patients.
Apr – 2011
Use of platelet-rich plasma and hyaluronic Acid in the loss of substance with bone exposure.
Cervelli V, Lucarini L, Spallone D, Palla L, Colicchia GM, Gentile P, De Angelis B. Adv Skin Wound Care. 2011 Apr;24(4):176-81.
In lower-extremity surgery, the complex wound with bone exposure remains a challenging problem for the plastic surgeon. The purpose of this study was to describe a new therapeutic approach to stimulate the regeneration of the lower-extremity complex wounds based on a combined treatment composed of platelet-rich plasma (PRP) and hyaluronic acid (HA) dressing.
Nov – 2010
Application of enhanced stromal vascular fraction and fat grafting mixed with PRP in post-traumatic lower extremity ulcers.
Cervelli V, Gentile P, De Angelis B, Calabrese C, Di Stefani A, Scioli MG, Curcio BC, Felici M, Orlandi A. Stem Cell Res. 2010 Nov 30.
The authors presented their experience in regenerative surgery of post-traumatic lower extremity ulcers, evaluating the effects related to the use of Enhanced Stromal Vascular Fraction (e-SVF) and Fat Grafting with Platelet rich Plasma (PRP). The authors compared the results of two control groups.
Ago – 2010
Treatment of stable vitiligo hands by ReCell system: a preliminary report.
Cervelli V, Spallone D, Lucarini L, Palla L, Brinci L, De Angelis B. Eur Rev Med Pharmacol Sci. 2010 Aug;14(8):691-4.
The aim of this study was to prove the effectiveness of MatriDerm(®) combined with skin grafting versus skin grafting alone in post-traumatic wounds treatment. At the Department of Plastic and Reconstructive Surgery of the University of Rome Tor Vergata, we treated 60 patients.
Giu – 2010
The use of Matriderm and autologous skin grafting in the treatment of diabetic ulcers: a case report.
Cervelli V, Lucarini L, Cerretani C, Spallone D, Palla L, Brinci L, De Angelis B. Int Wound J. 2010 Aug;7(4):291-6. Epub 2010 Jun 8.
The aim of our case report was to analyse the results obtained with the Matriderm system and autologous skin grafting for the surgical treatment of diabetic ulcers. We recruited one patient with diabetic ulcers admitted at the Department of Plastic and Reconstructive Surgery, University of Rome ‘Tor Vergata’.
Mag – 2010
A case of labial fusion and urinary pseudo-incontinence in an elderly woman. A surgical treatment and a review.
Palla L, De Angelis B, Lucarini L, Spallone D, Palla G, Cervelli V. Eur Rev Med Pharmacol Sci. 2010 May;14(5):491-3. Review.
Labial fusion is defined as either partial or complete adherence of the labia minora, and also called vulvar fusion, adhesions of the labia minor or conglutination of the labia minora and sinechia of the vulva.
Mag – 2010
Use of platelet rich plasma and hyaluronic acid on exposed tendons of the foot and ankle.
Cervelli V, Lucarini L, Spallone D, Brinci L, de Angelis B. J Wound Care. 2010 May;19(5):186, 188-90.
Platelet rich plasma was used as an autologous scaffold for cellular growth, in combination with hyaluronic acid as a temporary dermal substitute. This aided healing of acute and chronic open wounds of the foot and ankle.
Giu – 2010
The use of Matriderm and autologous skin grafting in the treatment of diabetic ulcers: a case report.
Cervelli V, Lucarini L, Cerretani C, Spallone D, Palla L, Brinci L, De Angelis B. Int Wound J. 2010 Aug;7(4):291-6. Epub 2010 Jun 8.
The aim of our case report was to analyse the results obtained with the Matriderm system and autologous skin grafting for the surgical treatment of diabetic ulcers. We recruited one patient with diabetic ulcers admitted at the Department of Plastic and Reconstructive Surgery, University of Rome ‘Tor Vergata’.
Mag – 2010
A case of labial fusion and urinary pseudo-incontinence in an elderly woman. A surgical treatment and a review.
Palla L, De Angelis B, Lucarini L, Spallone D, Palla G, Cervelli V. Eur Rev Med Pharmacol Sci. 2010 May;14(5):491-3. Review.
Labial fusion is defined as either partial or complete adherence of the labia minora, and also called vulvar fusion, adhesions of the labia minor or conglutination of the labia minora and sinechia of the vulva.
Mag – 2010
Use of platelet rich plasma and hyaluronic acid on exposed tendons of the foot and ankle.
Cervelli V, Lucarini L, Spallone D, Brinci L, de Angelis B. J Wound Care. 2010 May;19(5):186, 188-90.
Platelet rich plasma was used as an autologous scaffold for cellular growth, in combination with hyaluronic acid as a temporary dermal substitute. This aided healing of acute and chronic open wounds of the foot and ankle.
Ott – 2010
Use of a novel autologous cell-harvesting device to promote epithelialization and enhance appropriate pigmentation in scar reconstruction.
Cervelli V, De Angelis B, Spallone D, Lucarini L, Arpino A, Balzani A. Clin Exp Dermatol. 2010 Oct;35(7):776-80.
Epidermal replacement is an important step in the management of patients with post-traumatic and iatrogenic scars. Skin-colour variation from disease or trauma causes significant changes in self-image and appearance.
Giu – 2010
Tissue regeneration in loss of substance on the lower limbs through use of platelet-rich plasma, stem cells from adipose tissue, and hyaluronic acid.
Cervelli V, De Angelis B, Lucarini L, Spallone D, Balzani A, Palla L, Gentile P, Cerulli P. Adv Skin Wound Care. 2010 Jun;23(6):262-72.
Platelet-rich plasma (PRP) induces wound regeneration and tissue repair through cell proliferation and differentiation, promoting tissue healing and also acting as an autologous scaffold.
2009
Treatment of stable vitiligo by ReCell system.
Cervelli V, De Angelis B, Balzani A, Colicchia G, Spallone D, Grimaldi M. Acta Dermatovenerol Croat. 2009;17(4):273-8.
The aim of our study was to analyze the results obtained with the ReCell system for surgical treatment of stable vitiligo. At Department of Plastic and Reconstructive surgery, University of Tor Vergata in Rome, we treated 15 patients with stable vitiligo during a 2-year period.
Set – 2007
A randomized trial comparing ReCell system of epidermal cells delivery versus classic skin grafts for the treatment of deep partial thickness burns.
Gravante G, Di Fede MC, Araco A, Grimaldi M, De Angelis B, Arpino A, Cervelli V, Montone A. Burns. 2007 Dec;33(8):966-72. Epub 2007 Sep 29.
Our purpose was to directly compare results obtained with the ReCell system and the classic skin grafting for epidermal replacement in deep partial thickness burns.
Mar – 2006
Traumas of the middle skull base with TMJ involvement. Case report.
Bottini DJ, Gnoni G, De Angelis B, Savo P, Trimarco A, Cervelli G, Cervelli V. Minerva Stomatol. 2006 Mar;55(3):151-7. English, Italian. Riv Chir Mano – Vol. 43 (3) 2006
The authors report their experience with temporomandibular joint (TMJ) traumas involving breakage of the roof of the glenoid cavity, an infrequent event that occurs in those cases in which, as a result of the condylar neck not fracturing, the traumatic energy is transmitted to the middle skull base.